Andrei Ivanovich Borisenko (Андрей Иванович Борисенко - born April 17, 1964 in Leningrad, Russia) is a Russian cosmonaut. He was selected as a cosmonaut in May 2003, and is a veteran of two long duration missions to the International Space Station.
Borisenko served as a flight engineer onboard Soyuz TMA-21 for Expedition 27, the 27th long-duration mission to the International Space Station (ISS). He also served as the commander of the International Space Station for Expedition 28. He launched for the second time in October 2016 onboard Soyuz MS-02 as a flight engineer of Expedition 49 and Expedition 50. He returned to Earth in April 2017.